Coumarins and derivatives
Apexbio Technology LLC Dicoumarol 66-76-2 100mg
Dicoumarol (CAS 66-76-2) is a small molecule inhibitor targeting NAD(P)H quinone oxidoreductase 1 (NQO1) and pyruvate dehydrogenase kinase 1 (PDK1) exhibiting IC50 values of 0 37 M and 19 42 M respectively in vitro By inhibiting NQO1 Dicoumarol perturbs cellular redox homeostasis while its suppression of PDK1 modulates glycolytic flux and mitochondrial energy metabolism These actions make Dicoumarol a valuable tool for investigating tumor metabolism oxidative stress apoptosis and associated signaling pathways in biomedical research contexts
Apexbio Technology LLC 6,7-Dihydroxycoumarin 305-01-1 20mg
6 7-Dihydroxycoumarin (CAS 305-01-1) also known as esculetin is a naturally occurring coumarin derivative extracted from Aesculus hippocastanum Linn This compound exhibits notable antioxidant activity primarily by scavenging reactive oxygen species and inhibiting lipid peroxidation Additionally 6 7-dihydroxycoumarin has been studied for its modulatory effects on various cellular signaling pathways implicated in inflammation and apoptosis Its applications in biomedical research include investigations into oxidative stress inflammation and related disease models The compound is soluble in ethanol and dilute alkali and should be stored in a sealed cool and dry environment to preserve stability
Cayman Chemical CoumarIn BoronIc AcId 10mg
A fluorescent probe for direct detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide; reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s); COH displays ex/em = 332/470 nm, respectively
Cayman Chemical CoumarIn BoronIc AcId 50mg
A fluorescent probe for direct detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide; reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s); COH displays ex/em = 332/470 nm, respectively
Chem-Impex International, Inc. 7-Hydroxy-4-methylcoumarin | 90-33-5 | MFCD00006866 | 25G
7-Hydroxy-4-methylcoumarin, 90-33-5, MFCD00006866, 25G
Abcam 7-Amino-4-methylcoumarin, Fluorescent labeling reagent, 100MG
MW 175.18 Da, Purity >99%. Fluorescent probe to analyse glycoproteins' monosaccharides and N-linked oligosaccharides. Antibacterial and antifungal agent in vitro. Used for spectrophotometric determination of small amounts of nitrite.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Coumarin 334
Chemical. CAS 55804-67-6. Formula C17H17NO3. Molecular Weight 283.32. Coumarin 334 is a laser dye with an absorption maximum of 452nm. It is used as starting material for the synthesis of cysteine-selective or pH indicator fluorescent probes. Spectral data lambdamax 452nm, epsilon extinction coefficient >45000 at 449-455 nm in ethanol, lambdalaser 532nm.
Selleck Chemical LLC 7-Methylcoumarin-E0656-100MG
7-Methylcoumarin can inhibit the growth of S aureus and the growth of Gram-positive bacteria within a concentration of 0 8 3 6 g/ml and also has a strong hepatoprotective activity